Federation transports used in the mid 24th century.

USS Drake NCC-20381
   Destroyed by the automatic defense system in 2364.
   "Arsenal of Freedom" - TNG.
USS Fleming NCC-20316
   Lost in the Hekaras Corridor while carrying biomimetic gel in 2370. The crew of the Fleming was rescued by the USS Enterprise
however the ship was a complete loss.
   Named for Sir Alexander Fleming, the British bacteriologist who discovered penicillin.
   "Force of Nature" - TNG.